PDB 3ndm

PDB Information

PDB3NDM
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.
Bosanac, T., Hickey, E.R., Ginn, J., Kashem, M., Kerr, S., Kugler, S., Li, X., Olague, A., Schlyer, S., Young, E.R.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-06-07
Resolution3.300
CATH Insert Date23 Jan, 2011

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped
C 24 Jan, 2011 Chopped
D 24 Jan, 2011 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3ndmA01 17 Feb, 2011 3.30.200.20 Assigned
3ndmA02 17 Feb, 2011 1.10.510.10 Assigned
3ndmB01 17 Feb, 2011 3.30.200.20 Assigned
3ndmB02 17 Feb, 2011 1.10.510.10 Assigned
3ndmC01 17 Feb, 2011 3.30.200.20 Assigned
3ndmC02 17 Feb, 2011 1.10.510.10 Assigned
3ndmD01 17 Feb, 2011 3.30.200.20 Assigned
3ndmD02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1