PDB Information

PDB3N0H
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase.
Cody, V., Pace, J., Piraino, J., Queener, S.F.
J.Struct.Biol.
HeaderOxidoreductase
Released2010-05-14
Resolution1.920
CATH Insert Date02 Oct, 2011

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3n0hA00 01 Dec, 2011 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase