PDB Information

PDB3ML9
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design.
Cheng, H., Li, C., Bailey, S., Baxi, S.M., Goulet, L., Guo, L., Hoffman, J., Jiang, Y., Johnson, T.O., Johnson, T.W., Knighton, D.R., Li, J., Liu, K.K., Liu, Z., Marx, M.A., Walls, M., Wells, P.A., Yin, M.J., Zhu, J., Zientek, M.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2010-04-16
Resolution2.550
CATH Insert Date06 Jun, 2010

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jun, 2010 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3ml9A01 31 Jul, 2010 3.10.20.90 Assigned
3ml9A02 31 Jul, 2010 2.60.40.150 Assigned
3ml9A03 31 Jul, 2010 1.25.40.70 Assigned
3ml9A04 31 Jul, 2010 3.30.1010.10 Assigned
3ml9A05 31 Jul, 2010 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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