PDB Information

PDB3MJW
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
5-Ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-alpha and mTOR for the treatment of breast cancer.
Zhang, N., Ayral-Kaloustian, S., Anderson, J.T., Nguyen, T., Das, S., Venkatesan, A.M., Brooijmans, N., Lucas, J., Yu, K., Hollander, I., Mallon, R.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2010-04-13
Resolution2.870
CATH Insert Date13 Jun, 2010

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 13 Jun, 2010 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3mjwA01 31 Jul, 2010 3.10.20.90 Assigned
3mjwA02 31 Jul, 2010 2.60.40.150 Assigned
3mjwA03 31 Jul, 2010 1.25.40.70 Assigned
3mjwA04 31 Jul, 2010 3.30.1010.10 Assigned
3mjwA05 31 Jul, 2010 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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