PDB 3me3

PDB Information

PDB3ME3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Anastasiou, D., Yu, Y., Israelsen, W.J., Jiang, J.K., Boxer, M.B., Hong, B.S., Tempel, W., Dimov, S., Shen, M., Jha, A., Yang, H., Mattaini, K.R., Metallo, C.M., Fiske, B.P., Courtney, K.D., Malstrom, S., Khan, T.M., Kung, C., Skoumbourdis, A.P., Veith, H., Southall, N., Walsh, M.J., Brimacombe, K.R., Leister, W., Lunt, S.Y., Johnson, Z.R., Yen, K.E., Kunii, K., Davidson, S.M., Christofk, H.R., Austin, C.P., Inglese, J., Harris, M.H., Asara, J.M., Stephanopoulos, G., Salituro, F.G., Jin, S., Dang, L., Auld, D.S., Park, H.W., Cantley, L.C., Thomas, C.J., Vander Heiden, M.G.
Nat.Chem.Biol.
HeaderTransferase
Released2010-03-31
Resolution1.950
CATH Insert Date02 May, 2010

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 May, 2010 Chopped
B 03 May, 2010 Chopped
C 03 May, 2010 Chopped
D 03 May, 2010 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3me3A01 08 Feb, 2013 3.40.1380.20 Assigned
3me3A02 08 Feb, 2013 3.20.20.60 Assigned
3me3A03 08 Feb, 2013 2.40.33.10 Assigned
3me3B01 08 Feb, 2013 3.40.1380.20 Assigned
3me3B02 08 Feb, 2013 3.20.20.60 Assigned
3me3B03 08 Feb, 2013 2.40.33.10 Assigned
3me3C01 08 Feb, 2013 3.40.1380.20 Assigned
3me3C02 08 Feb, 2013 3.20.20.60 Assigned
3me3C03 08 Feb, 2013 2.40.33.10 Assigned
3me3D01 08 Feb, 2013 3.40.1380.20 Assigned
3me3D02 08 Feb, 2013 3.20.20.60 Assigned
3me3D03 08 Feb, 2013 2.40.33.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM