PDB 3me3

PDB	3ME3
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Anastasiou, D., Yu, Y., Israelsen, W.J., Jiang, J.K., Boxer, M.B., Hong, B.S., Tempel, W., Dimov, S., Shen, M., Jha, A., Yang, H., Mattaini, K.R., Metallo, C.M., Fiske, B.P., Courtney, K.D., Malstrom, S., Khan, T.M., Kung, C., Skoumbourdis, A.P., Veith, H., Southall, N., Walsh, M.J., Brimacombe, K.R., Leister, W., Lunt, S.Y., Johnson, Z.R., Yen, K.E., Kunii, K., Davidson, S.M., Christofk, H.R., Austin, C.P., Inglese, J., Harris, M.H., Asara, J.M., Stephanopoulos, G., Salituro, F.G., Jin, S., Dang, L., Auld, D.S., Park, H.W., Cantley, L.C., Thomas, C.J., Vander Heiden, M.G. Nat.Chem.Biol.
Header	Transferase
Released	2010-03-31
Resolution	1.950
CATH Insert Date	02 May, 2010

PDB 3me3

PDB Chain 3me3A

PDB Chain 3me3B

PDB Chain 3me3C

PDB Chain 3me3D

CATH Domain 3me3A01

CATH Domain 3me3A02

CATH Domain 3me3A03

CATH Domain 3me3B01

CATH Domain 3me3B02

CATH Domain 3me3B03

CATH Domain 3me3C01

CATH Domain 3me3C02

CATH Domain 3me3C03

CATH Domain 3me3D01

CATH Domain 3me3D02

CATH Domain 3me3D03

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3me3A01	08 Feb, 2013	3.40.1380.20	Assigned
3me3A02	08 Feb, 2013	3.20.20.60	Assigned
3me3A03	08 Feb, 2013	2.40.33.10	Assigned
3me3B01	08 Feb, 2013	3.40.1380.20	Assigned
3me3B02	08 Feb, 2013	3.20.20.60	Assigned
3me3B03	08 Feb, 2013	2.40.33.10	Assigned
3me3C01	08 Feb, 2013	3.40.1380.20	Assigned
3me3C02	08 Feb, 2013	3.20.20.60	Assigned
3me3C03	08 Feb, 2013	2.40.33.10	Assigned
3me3D01	08 Feb, 2013	3.40.1380.20	Assigned
3me3D02	08 Feb, 2013	3.20.20.60	Assigned
3me3D03	08 Feb, 2013	2.40.33.10	Assigned

Accession	Gene ID	Taxon	Description
P14618	KPYM_HUMAN	Homo sapiens	Pyruvate kinase PKM
P14618	KPYM_HUMAN	Homo sapiens	Pyruvate kinase PKM
P14618	KPYM_HUMAN	Homo sapiens	Pyruvate kinase PKM
P14618	KPYM_HUMAN	Homo sapiens	Pyruvate kinase PKM