PDB 3lpj

PDB Information

PDB3LPJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization.
Cumming, J., Babu, S., Huang, Y., Carrol, C., Chen, X., Favreau, L., Greenlee, W., Guo, T., Kennedy, M., Kuvelkar, R., Le, T., Li, G., McHugh, N., Orth, P., Ozgur, L., Parker, E., Saionz, K., Stamford, A., Strickland, C., Tadesse, D., Voigt, J., Zhang, L., Zhang, Q.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2010-02-05
Resolution1.790
CATH Insert Date18 Apr, 2010

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2010 Chopped
B 18 Apr, 2010 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3lpjA01 21 Jul, 2010 2.40.70.10 Assigned
3lpjA02 21 Jul, 2010 2.40.70.10 Assigned
3lpjB01 21 Jul, 2010 2.40.70.10 Assigned
3lpjB02 21 Jul, 2010 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1