PDB 3lhj

PDB Information

PDB3LHJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase.
Pettus, L.H., Wurz, R.P., Xu, S., Herberich, B., Henkle, B., Liu, Q., McBride, H.J., Mu, S., Plant, M.H., Saris, C.J., Sherman, L., Wong, L.M., Chmait, S., Lee, M.R., Mohr, C., Hsieh, F., Tasker, A.S.
J.Med.Chem.
HeaderTransferase
Released2010-01-22
Resolution3.310
CATH Insert Date18 Apr, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3lhjA01 09 Jul, 2010 3.30.200.20 Assigned
3lhjA02 09 Jul, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
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