PDB 3l3a

PDB Information

PDB3L3A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Malamas, M.S., Barnes, K., Hui, Y., Johnson, M., Lovering, F., Condon, J., Fobare, W., Solvibile, W., Turner, J., Hu, Y., Manas, E.S., Fan, K., Olland, A., Chopra, R., Bard, J., Pangalos, M.N., Reinhart, P., Robichaud, A.J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-12-16
Resolution2.360
CATH Insert Date02 May, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 May, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3l3aA01 02 Jul, 2010 2.40.70.10 Assigned
3l3aA02 02 Jul, 2010 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1