PDB Information

PDB3KWZ
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors
Rankovic, Z., Cai, J., Kerr, J., Fradera, X., Robinson, J., Mistry, A., Hamilton, E., McGarry, G., Andrews, F., Caulfield, W., Cumming, I., Dempster, M., Waller, J., Scullion, P., Martin, I., Mitchell, A., Long, C., Baugh, M., Westwood, P., Kinghorn, E., Bruin, J., Hamilton, W., Uitdehaag, J., van Zeeland, M., Potin, D., Saniere, L., Fouquet, A., Chevallier, F., Deronzier, H., Dorleans, C., Nicolai, E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-12-02
Resolution1.490
CATH Insert Date04 Mar, 2010

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2010 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3kwzA00 29 Jun, 2010 3.90.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43235 CATK_HUMAN Homo sapiens Cathepsin K
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