PDB Information

PDB3KW9
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors.
Rankovic, Z., Cai, J., Kerr, J., Fradera, X., Robinson, J., Mistry, A., Hamilton, E., McGarry, G., Andrews, F., Caulfield, W., Cumming, I., Dempster, M., Waller, J., Scullion, P., Martin, I., Mitchell, A., Long, C., Baugh, M., Westwood, P., Kinghorn, E., Bruin, J., Hamilton, W., Uitdehaag, J., van Zeeland, M., Potin, D., Saniere, L., Fouquet, A., Chevallier, F., Deronzier, H., Dorleans, C., Nicolai, E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-12-01
Resolution1.800
CATH Insert Date04 Mar, 2010

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2010 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3kw9A00 28 Jun, 2010 3.90.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43235 CATK_HUMAN Homo sapiens Cathepsin K
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