PDB Information

PDB3KCF
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Pyrazolone based TGFbetaR1 kinase inhibitors.
Guckian, K., Carter, M.B., Lin, E.Y., Choi, M., Sun, L., Boriack-Sjodin, P.A., Chuaqui, C., Lane, B., Cheung, K., Ling, L., Lee, W.C.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-10-21
Resolution2.800
CATH Insert Date24 Dec, 2009

PDB Images (16)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 25 Dec, 2009 Chopped
B 25 Dec, 2009 Chopped
C 25 Dec, 2009 Chopped
D 25 Dec, 2009 Chopped
E 25 Dec, 2009 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
3kcfA01 15 Apr, 2010 3.30.200.20 Assigned
3kcfA02 15 Apr, 2010 1.10.510.10 Assigned
3kcfB01 15 Apr, 2010 3.30.200.20 Assigned
3kcfB02 15 Apr, 2010 1.10.510.10 Assigned
3kcfC01 15 Apr, 2010 3.30.200.20 Assigned
3kcfC02 15 Apr, 2010 1.10.510.10 Assigned
3kcfD01 15 Apr, 2010 3.30.200.20 Assigned
3kcfD02 15 Apr, 2010 1.10.510.10 Assigned
3kcfE01 15 Apr, 2010 3.30.200.20 Assigned
3kcfE02 15 Apr, 2010 1.10.510.10 Assigned

UniProtKB Entries (5)

Accession Gene ID Taxon Description
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1