PDB 3k98

PDB Information

PDB3K98
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone.
Kung, P.P., Huang, B., Zhang, G., Zhou, J.Z., Wang, J., Digits, J.A., Skaptason, J., Yamazaki, S., Neul, D., Zientek, M., Elleraas, J., Mehta, P., Yin, M.J., Hickey, M.J., Gajiwala, K.S., Rodgers, C., Davies, J.F., Gehring, M.R.
J.Med.Chem.
HeaderChaperone
Released2009-10-15
Resolution2.400
CATH Insert Date11 Feb, 2010

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Feb, 2010 Chopped
B 11 Feb, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3k98A00 14 Apr, 2010 3.30.565.10 Assigned
3k98B00 14 Apr, 2010 3.30.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha