PDB Information

PDB3K22
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor.
Biggadike, K., Bledsoe, R.K., Coe, D.M., Cooper, T.W., House, D., Iannone, M.A., Macdonald, S.J., Madauss, K.P., McLay, I.M., Shipley, T.J., Taylor, S.J., Tran, T.B., Uings, I.J., Weller, V., Williams, S.P.
Proc.Natl.Acad.Sci.USA
HeaderTranscription
Released2009-09-29
Resolution2.100
CATH Insert Date15 Aug, 2010

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped
D 16 Aug, 2010 Rejected
H 16 Aug, 2010 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3k22A00 12 Jun, 2012 1.10.565.10 Assigned
3k22B00 12 Jun, 2012 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
P04150 GCR_HUMAN Homo sapiens Glucocorticoid receptor
P04150 GCR_HUMAN Homo sapiens Glucocorticoid receptor
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2