PDB Information

PDB3IW4
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes
Wagner, J., von Matt, P., Sedrani, R., Albert, R., Cooke, N., Ehrhardt, C., Geiser, M., Rummel, G., Stark, W., Strauss, A., Cowan-Jacob, S.W., Beerli, C., Weckbecker, G., Evenou, J.P., Zenke, G., Cottens, S.
J.Med.Chem.
HeaderTransferase
Released2009-09-02
Resolution2.800
CATH Insert Date15 Nov, 2009

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2009 Chopped
B 15 Nov, 2009 Chopped
C 15 Nov, 2009 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3iw4A01 05 Apr, 2010 3.30.200.20 Assigned
3iw4A02 05 Apr, 2010 1.10.510.10 Assigned
3iw4B01 05 Apr, 2010 3.30.200.20 Assigned
3iw4B02 05 Apr, 2010 1.10.510.10 Assigned
3iw4C01 05 Apr, 2010 3.30.200.20 Assigned
3iw4C02 05 Apr, 2010 1.10.510.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P17252 KPCA_HUMAN Homo sapiens Protein kinase C alpha type
P17252 KPCA_HUMAN Homo sapiens Protein kinase C alpha type
P17252 KPCA_HUMAN Homo sapiens Protein kinase C alpha type