PDB 3itz

PDB Information

PDB3ITZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.
Wurz, R.P., Pettus, L.H., Henkle, B., Sherman, L., Plant, M., Miner, K., McBride, H.J., Wong, L.M., Saris, C.J., Lee, M.R., Chmait, S., Mohr, C., Hsieh, F., Tasker, A.S.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-08-28
Resolution2.250
CATH Insert Date04 Mar, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3itzA01 04 Apr, 2010 3.30.200.20 Assigned
3itzA02 04 Apr, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14