PDB 3inh

PDB Information

PDB3INH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors.
Malamas, M.S., Erdei, J., Gunawan, I., Turner, J., Hu, Y., Wagner, E., Fan, K., Chopra, R., Olland, A., Bard, J., Jacobsen, S., Magolda, R.L., Pangalos, M., Robichaud, A.J.
J.Med.Chem.
HeaderHydrolase
Released2009-08-12
Resolution1.800
CATH Insert Date04 Mar, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3inhA01 01 Apr, 2010 2.40.70.10 Assigned
3inhA02 01 Apr, 2010 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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