PDB Information

PDB3IEC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates.
Nesic, D., Miller, M.C., Quinkert, Z.T., Stein, M., Chait, B.T., Stebbins, C.E.
Nat.Struct.Mol.Biol.
HeaderSignaling Protein/Toxin
Released2009-07-22
Resolution2.200
CATH Insert Date10 Dec, 2009

PDB Images (21)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 10 Dec, 2009 Chopped
B 10 Dec, 2009 Chopped
C 10 Dec, 2009 Chopped
D 10 Dec, 2009 Chopped
E 10 Dec, 2009 Rejected
F 10 Dec, 2009 Rejected
G 10 Dec, 2009 Rejected
H 10 Dec, 2009 Rejected

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3iecA01 16 Aug, 2010 3.30.200.20 Assigned
3iecA02 16 Aug, 2010 1.10.510.10 Assigned
3iecA03 16 Aug, 2010 1.10.8.10 Assigned
3iecB01 16 Aug, 2010 3.30.200.20 Assigned
3iecB02 16 Aug, 2010 1.10.510.10 Assigned
3iecB03 16 Aug, 2010 1.10.8.10 Assigned
3iecC01 16 Aug, 2010 3.30.200.20 Assigned
3iecC02 16 Aug, 2010 1.10.510.10 Assigned
3iecC03 16 Aug, 2010 1.10.8.10 Assigned
3iecD01 16 Aug, 2010 3.30.200.20 Assigned
3iecD02 16 Aug, 2010 1.10.510.10 Assigned
3iecD03 16 Aug, 2010 1.10.8.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q7KZI7 MARK2_HUMAN Homo sapiens Serine/threonine-protein kinase MARK2
P55980 CAGA_HELPY Helicobacter pylori 26695 Cytotoxicity-associated immunodominant antigen
P55980 CAGA_HELPY Helicobacter pylori 26695 Cytotoxicity-associated immunodominant antigen
P55980 CAGA_HELPY Helicobacter pylori 26695 Cytotoxicity-associated immunodominant antigen
Q7KZI7 MARK2_HUMAN Homo sapiens Serine/threonine-protein kinase MARK2
Q7KZI7 MARK2_HUMAN Homo sapiens Serine/threonine-protein kinase MARK2
Q7KZI7 MARK2_HUMAN Homo sapiens Serine/threonine-protein kinase MARK2
P55980 CAGA_HELPY Helicobacter pylori 26695 Cytotoxicity-associated immunodominant antigen
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