Discovery of a 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitor (BMS-754807) of insulin-like growth factor receptor (IGF-1R) kinase in clinical development.
Wittman, M.D., Carboni, J.M., Yang, Z., Lee, F.Y., Antman, M., Attar, R., Balimane, P., Chang, C., Chen, C., Discenza, L., Frennesson, D., Gottardis, M.M., Greer, A., Hurlburt, W., Johnson, W., Langley, D.R., Li, A., Li, J., Liu, P., Mastalerz, H., Mathur, A., Menard, K., Patel, K., Sack, J., Sang, X., Saulnier, M., Smith, D., Stefanski, K., Trainor, G., Velaparthi, U., Zhang, G., Zimmermann, K., Vyas, D.M.
J.Med.Chem.
