PDB 3i5z

PDB Information

PDB3I5Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control.
Aronov, A.M., Tang, Q., Martinez-Botella, G., Bemis, G.W., Cao, J., Chen, G., Ewing, N.P., Ford, P.J., Germann, U.A., Green, J., Hale, M.R., Jacobs, M., Janetka, J.W., Maltais, F., Markland, W., Namchuk, M.N., Nanthakumar, S., Poondru, S., Straub, J., ter Haar, E., Xie, X.
J.Med.Chem.
HeaderTransferase
Released2009-07-06
Resolution2.200
CATH Insert Date14 Jan, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Jan, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3i5zA01 13 Mar, 2010 3.30.200.20 Assigned
3i5zA02 13 Mar, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
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