PDB Information

PDB3HW1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays
Godemann, R., Madden, J., Kramer, J., Smith, M.A., Fritz, U., Hesterkamp, T., Barker, J., Hoeppner, S., Hallett, D., Cesura, A., Ebneth, A., Kemp, J.
Biochemistry
HeaderHydrolase
Released2009-06-17
Resolution2.480
CATH Insert Date15 Nov, 2009

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2009 Chopped
B 15 Nov, 2009 Chopped
C 15 Nov, 2009 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3hw1A01 07 Mar, 2010 2.40.70.10 Assigned
3hw1A02 07 Mar, 2010 2.40.70.10 Assigned
3hw1B01 07 Mar, 2010 2.40.70.10 Assigned
3hw1B02 07 Mar, 2010 2.40.70.10 Assigned
3hw1C01 07 Mar, 2010 2.40.70.10 Assigned
3hw1C02 07 Mar, 2010 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1