PDB 3hhm

PDB Links
Overview

PDB Information

PDB	3HHM
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Mandelker, D., Gabelli, S.B., Schmidt-Kittler, O., Zhu, J., Cheong, I., Huang, C.H., Kinzler, K.W., Vogelstein, B., Amzel, L.M. Proc.Natl.Acad.Sci.USA
Header	Transferase/Oncoprotein
Released	2009-05-15
Resolution	2.800
CATH Insert Date	01 Oct, 2009

PDB Images (11)

Image of CATH 3hhm

3hhm

PDB 3hhm

Image of CATH 3hhmA

3hhmA

PDB Chain 3hhmA

Image of CATH 3hhmB

3hhmB

PDB Chain 3hhmB

Image of CATH 3hhmA01

3hhmA01

CATH Domain 3hhmA01

Image of CATH 3hhmA02

3hhmA02

CATH Domain 3hhmA02

Image of CATH 3hhmA03

3hhmA03

CATH Domain 3hhmA03

Image of CATH 3hhmA04

3hhmA04

CATH Domain 3hhmA04

Image of CATH 3hhmA05

3hhmA05

CATH Domain 3hhmA05

Image of CATH 3hhmA06

3hhmA06

CATH Domain 3hhmA06

Image of CATH 3hhmB01

3hhmB01

CATH Domain 3hhmB01

Image of CATH 3hhmB02

3hhmB02

CATH Domain 3hhmB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	01 Oct, 2009	Chopped
B	01 Oct, 2009	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3hhmA01	04 Sep, 2013	3.10.20.90	Assigned
3hhmA02	04 Sep, 2013	1.25.40.70	Assigned
3hhmA03	04 Sep, 2013	3.10.20.90	Assigned
3hhmA04	04 Sep, 2013	2.60.40.150	Assigned
3hhmA05	04 Sep, 2013	3.30.1010.10	Assigned
3hhmA06	04 Sep, 2013	1.10.1070.11	Assigned
3hhmB01	18 Aug, 2010	3.30.505.10	Assigned
3hhmB02	18 Aug, 2010	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform