PDB 3hec

PDB Information

PDB3HEC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases.
Namboodiri, H.V., Bukhtiyarova, M., Ramcharan, J., Karpusas, M., Lee, Y., Springman, E.B.
Biochemistry
HeaderTransferase
Released2009-05-08
Resolution2.500
CATH Insert Date15 Nov, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3hecA01 11 Feb, 2010 3.30.200.20 Assigned
3hecA02 11 Feb, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
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