PDB 3hc8

PDB Information

PDB3HC8
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system.
Hughes, R.O., Walker, J.K., Cubbage, J.W., Fobian, Y.M., Rogier, D.J., Heasley, S.E., Blevis-Bal, R.M., Benson, A.G., Owen, D.R., Jacobsen, E.J., Freskos, J.N., Molyneaux, J.M., Brown, D.L., Stallings, W.C., Acker, B.A., Maddux, T.M., Tollefson, M.B., Williams, J.M., Moon, J.B., Mischke, B.V., Rumsey, J.M., Zheng, Y., Macinnes, A., Bond, B.R., Yu, Y.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-05-05
Resolution1.790
CATH Insert Date16 Aug, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3hc8A00 10 Feb, 2010 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27815 PDE4A_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4A
O76074 PDE5A_HUMAN Homo sapiens cGMP-specific 3',5'-cyclic phosphodiesterase
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