PDB 3hc5

PDB Information

PDB3HC5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
FXR agonist activity of conformationally constrained analogs of GW 4064.
Akwabi-Ameyaw, A., Bass, J.Y., Caldwell, R.D., Caravella, J.A., Chen, L., Creech, K.L., Deaton, D.N., Madauss, K.P., Marr, H.B., McFadyen, R.B., Miller, A.B., Navas, F., Parks, D.J., Spearing, P.K., Todd, D., Williams, S.P., Bruce Wisely, G.
Bioorg.Med.Chem.Lett.
HeaderTranscription
Released2009-05-05
Resolution2.600
CATH Insert Date16 Aug, 2009

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3hc5A00 10 Feb, 2010 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
Q96RI1 NR1H4_HUMAN Homo sapiens Bile acid receptor