PDB Information

PDB3H3C
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity.
Walker, D.P., Zawistoski, M.P., McGlynn, M.A., Li, J.C., Kung, D.W., Bonnette, P.C., Baumann, A., Buckbinder, L., Houser, J.A., Boer, J., Mistry, A., Han, S., Xing, L., Guzman-Perez, A.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-04-16
Resolution2.000
CATH Insert Date16 Aug, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3h3cA01 09 Aug, 2010 3.30.200.20 Assigned
3h3cA02 09 Aug, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q14289 FAK2_HUMAN Homo sapiens Protein-tyrosine kinase 2-beta
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