PDB 3ghw

PDB Information

PDB3GHW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents
Gangjee, A., Li, W., Kisliuk, R.L., Cody, V., Pace, J., Piraino, J., Makin, J.
J.Med.Chem.
HeaderOxidoreductase
Released2009-03-04
Resolution1.240
CATH Insert Date24 Sep, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Sep, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3ghwA00 25 Dec, 2009 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase
CATH-Gene3D is a Global Biodata Core Resource Learn more...