PDB 3ghc

PDB Information

PDB3GHC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents
Gangjee, A., Li, W., Kisliuk, R.L., Cody, V., Pace, J., Piraino, J., Makin, J.
J.Med.Chem.
HeaderOxidoreductase
Released2009-03-03
Resolution1.300
CATH Insert Date24 Sep, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Sep, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3ghcA00 25 Dec, 2009 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase