PDB 3gfe

PDB Information

PDB3GFE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.
Wurz, R.P., Pettus, L.H., Xu, S., Henkle, B., Sherman, L., Plant, M., Miner, K., McBride, H., Wong, L.M., Saris, C.J., Lee, M.R., Chmait, S., Mohr, C., Hsieh, F., Tasker, A.S.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-02-26
Resolution2.100
CATH Insert Date16 Aug, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3gfeA01 24 Dec, 2009 3.30.200.20 Assigned
3gfeA02 24 Dec, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
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