PDB Information

PDB3G5E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
Van Zandt, M.C., Doan, B., Sawicki, D.R., Sredy, J., Podjarny, A.D.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2009-02-05
Resolution1.800
CATH Insert Date16 Aug, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3g5eA00 14 Dec, 2009 3.20.20.100 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P15121 ALDR_HUMAN Homo sapiens Aldo-keto reductase family 1 member B1
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