PDB 3fal

PDB Information

PDB3FAL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.
Chao, E.Y., Caravella, J.A., Watson, M.A., Campobasso, N., Ghisletti, S., Billin, A.N., Galardi, C., Wang, P., Laffitte, B.A., Iannone, M.A., Goodwin, B.J., Nichols, J.A., Parks, D.J., Stewart, E., Wiethe, R.W., Williams, S.P., Smallwood, A., Pearce, K.H., Glass, C.K., Willson, T.M., Zuercher, W.J., Collins, J.L.
J.Med.Chem.
HeaderSignaling Protein
Released2008-11-17
Resolution2.360
CATH Insert Date16 Aug, 2009

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
C 16 Aug, 2009 Chopped
D 16 Aug, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3falA00 18 Mar, 2013 1.10.565.10 Assigned
3falB00 08 Oct, 2009 1.10.565.10 Assigned
3falC00 18 Mar, 2013 1.10.565.10 Assigned
3falD00 08 Oct, 2009 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P19793 RXRA_HUMAN Homo sapiens Retinoic acid receptor RXR-alpha
Q9Z0Y9 NR1H3_MOUSE Mus musculus Oxysterols receptor LXR-alpha
P19793 RXRA_HUMAN Homo sapiens Retinoic acid receptor RXR-alpha
Q9Z0Y9 NR1H3_MOUSE Mus musculus Oxysterols receptor LXR-alpha