PDB Information

PDB3F82
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily
Schroeder, G.M., An, Y., Cai, Z.W., Chen, X.T., Clark, C., Cornelius, L.A., Dai, J., Gullo-Brown, J., Gupta, A., Henley, B., Hunt, J.T., Jeyaseelan, R., Kamath, A., Kim, K., Lippy, J., Lombardo, L.J., Manne, V., Oppenheimer, S., Sack, J.S., Schmidt, R.J., Shen, G., Stefanski, K., Tokarski, J.S., Trainor, G.L., Wautlet, B.S., Wei, D., Williams, D.K., Zhang, Y., Zhang, Y., Fargnoli, J., Borzilleri, R.M.
J.Med.Chem.
HeaderTransferase
Released2008-11-11
Resolution2.500
CATH Insert Date16 Aug, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3f82A01 08 Oct, 2009 3.30.200.20 Assigned
3f82A02 08 Oct, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
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