PDB 3f2a

PDB Information

PDB3F2A
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.
Qian, K., Wang, L., Cywin, C.L., Farmer, B.T., Hickey, E., Homon, C., Jakes, S., Kashem, M.A., Lee, G., Leonard, S., Li, J., Magboo, R., Mao, W., Pack, E., Peng, C., Prokopowicz, A., Welzel, M., Wolak, J., Morwick, T.
J.Med.Chem.
HeaderTransferase
Released2008-10-29
Resolution1.900
CATH Insert Date12 Mar, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 12 Mar, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3f2aA01 13 Mar, 2009 3.30.200.20 Assigned
3f2aA02 13 Mar, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1
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