PDB Information

PDB3EIG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.
Volpato, J.P., Yachnin, B.J., Blanchet, J., Guerrero, V., Poulin, L., Fossati, E., Berghuis, A.M., Pelletier, J.N.
J.Biol.Chem.
HeaderOxidoreductase
Released2008-09-15
Resolution1.700
CATH Insert Date16 Aug, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3eigA00 29 Sep, 2009 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase
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