PDB 3dv5

PDB Information

PDB3DV5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo.
Machauer, R., Laumen, K., Veenstra, S., Rondeau, J.M., Tintelnot-Blomley, M., Betschart, C., Jaton, A.L., Desrayaud, S., Staufenbiel, M., Rabe, S., Paganetti, P., Neumann, U.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2008-07-18
Resolution2.100
CATH Insert Date26 Feb, 2009

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 26 Feb, 2009 Chopped
B 26 Feb, 2009 Chopped
C 26 Feb, 2009 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3dv5A01 03 Mar, 2009 2.40.70.10 Assigned
3dv5A02 03 Mar, 2009 2.40.70.10 Assigned
3dv5B01 03 Mar, 2009 2.40.70.10 Assigned
3dv5B02 03 Mar, 2009 2.40.70.10 Assigned
3dv5C01 03 Mar, 2009 2.40.70.10 Assigned
3dv5C02 03 Mar, 2009 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1