SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Buchanan, S.G., Hendle, J., Lee, P.S., Smith, C.R., Bounaud, P.Y., Jessen, K.A., Tang, C.M., Huser, N.H., Felce, J.D., Froning, K.J., Peterman, M.C., Aubol, B.E., Gessert, S.F., Sauder, J.M., Schwinn, K.D., Russell, M., Rooney, I.A., Adams, J., Leon, B.C., Do, T.H., Blaney, J.M., Sprengeler, P.A., Thompson, D.A., Smyth, L., Pelletier, L.A., Atwell, S., Holme, K., Wasserman, S.R., Emtage, S., Burley, S.K., Reich, S.H.
Mol.Cancer Ther.