PDB 3cwe

PDB Information

PDB3CWE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
Han, Y., Belley, M., Bayly, C.I., Colucci, J., Dufresne, C., Giroux, A., Lau, C.K., Leblanc, Y., McKay, D., Therien, M., Wilson, M.C., Skorey, K., Chan, C.C., Scapin, G., Kennedy, B.P.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2008-04-21
Resolution1.600
CATH Insert Date23 Jul, 2008

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3cweA00 25 Jul, 2008 3.90.190.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P18031 PTN1_HUMAN Homo sapiens Tyrosine-protein phosphatase non-receptor type 1
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