PDB Information

PDB3CD5
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.
Sarver, R.W., Bills, E., Bolton, G., Bratton, L.D., Caspers, N.L., Dunbar, J.B., Harris, M.S., Hutchings, R.H., Kennedy, R.M., Larsen, S.D., Pavlovsky, A., Pfefferkorn, J.A., Bainbridge, G.
J.Med.Chem.
HeaderOxidoreductase
Released2008-02-26
Resolution2.390
CATH Insert Date23 Jul, 2008

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3cd5A01 26 Jul, 2008 1.10.3270.10 Assigned
3cd5A02 26 Jul, 2008 3.90.770.10 Assigned
3cd5A03 26 Jul, 2008 3.30.70.420 Assigned
3cd5B01 25 Jul, 2008 1.10.3270.10 Assigned
3cd5B02 25 Jul, 2008 3.90.770.10 Assigned
3cd5B03 25 Jul, 2008 3.30.70.420 Assigned
3cd5C01 26 Jul, 2008 1.10.3270.10 Assigned
3cd5C02 26 Jul, 2008 3.90.770.10 Assigned
3cd5C03 26 Jul, 2008 3.30.70.420 Assigned
3cd5D01 26 Jul, 2008 1.10.3270.10 Assigned
3cd5D02 26 Jul, 2008 3.90.770.10 Assigned
3cd5D03 26 Jul, 2008 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
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