PDB 3ccw

PDB Information

PDB3CCW
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.
Sarver, R.W., Bills, E., Bolton, G., Bratton, L.D., Caspers, N.L., Dunbar, J.B., Harris, M.S., Hutchings, R.H., Kennedy, R.M., Larsen, S.D., Pavlovsky, A., Pfefferkorn, J.A., Bainbridge, G.
J.Med.Chem.
HeaderOxidoreductase
Released2008-02-26
Resolution2.100
CATH Insert Date23 Jul, 2008

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3ccwA01 26 Jul, 2008 1.10.3270.10 Assigned
3ccwA02 26 Jul, 2008 3.90.770.10 Assigned
3ccwA03 26 Jul, 2008 3.30.70.420 Assigned
3ccwB01 26 Jul, 2008 1.10.3270.10 Assigned
3ccwB02 26 Jul, 2008 3.90.770.10 Assigned
3ccwB03 26 Jul, 2008 3.30.70.420 Assigned
3ccwC01 26 Jul, 2008 1.10.3270.10 Assigned
3ccwC02 26 Jul, 2008 3.90.770.10 Assigned
3ccwC03 26 Jul, 2008 3.30.70.420 Assigned
3ccwD01 26 Jul, 2008 1.10.3270.10 Assigned
3ccwD02 26 Jul, 2008 3.90.770.10 Assigned
3ccwD03 26 Jul, 2008 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
CATH-Gene3D is a Global Biodata Core Resource Learn more...