PDB 3arn
PDB Information
PDB | 3ARN |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2010-12-03 |
Resolution | 1.800 |
CATH Insert Date | 23 Jan, 2011 |
PDB Images (7)
PDB Prints
PDB Chains (3)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 24 Jan, 2011 | Chopped |
B | 24 Jan, 2011 | Chopped |
C | 24 Jan, 2011 | Chopped |
CATH Domains (3)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
3arnA00 | 12 Jul, 2011 | 2.70.40.10 | Assigned |
3arnB00 | 12 Jul, 2011 | 2.70.40.10 | Assigned |
3arnC00 | 12 Jul, 2011 | 2.70.40.10 | Assigned |
UniProtKB Entries (3)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P33316 | DUT_HUMAN | Homo sapiens | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
P33316 | DUT_HUMAN | Homo sapiens | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
P33316 | DUT_HUMAN | Homo sapiens | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |