PDB Information

PDB2YHV
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib.
Huang, Q., Johnson, T.W., Bailey, S., Brooun, A., Bunker, K.D., Burke, B.J., Collins, M.R., Cook, A.S., Cui, J.J., Dack, K.N., Deal, J.G., Deng, Y., Dinh, D., Engstrom, L.D., He, M., Hoffman, J., Hoffman, R.L., Johnson, P.S., Kania, R.S., Lam, H., Lam, J.L., Le, P.T., Li, Q., Lingardo, L., Liu, W., Lu, M.W., Mctigue, M., Palmer, C.L., Richardson, P.F., Sach, N.W., Shen, H., Smeal, T., Smith, G.L., Stewart, A.E., Timofeevski, S., Tsaparikos, K., Wang, H., Zhu, H., Zhu, J., Zou, H.Y., Edwards, M.P.
J.Med.Chem.
HeaderTransferase
Released2011-05-06
Resolution1.900
CATH Insert Date22 May, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 23 May, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2yhvA01 26 May, 2011 3.30.200.20 Assigned
2yhvA02 26 May, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor
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