Discovery of (7R)-14-Cyclohexyl-7-{[2-(Dimethylamino)Ethyl] (Methyl)Amino}-7,8-Dihydro-6H-Indolo[1,2-E][1,5] Benzoxazocine -11-Carboxylic Acid (Mk-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus Ns5B Polymerase
Narjes, F., Crescenzi, B., Ferrara, M., Habermann, J., Colarusso, S., Del Rosario Rico Ferreira, M., Stansfield, I., Mackay, A.C., Conte, I., Ercolani, C., Zaramella, S., Palumbi, M.C., Meuleman, P., Leroux-Roels, G., Giuliano, C., Fiore, F., Di Marco, S., Baiocco, P., Koch, U., Migliaccio, G., Altamura, S., Laufer, R., De Francesco, R., Rowley, M.
J.Med.Chem.
