Discovery of (2,4-Dihydroxy-5-Isopropylphenyl)-[5-(4-Methylpiperazin-1-Ylmethyl)-1,3-Dihydroisoindol-2-Yl]Methanone (at13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design.
Woodhead, A.J., Angove, H., Carr, M.G., Chessari, G., Congreve, M., Coyle, J.E., Cosme, J., Graham, B., Day, P.J., Downham, R., Fazal, L., Feltell, R., Figueroa, E., Frederickson, M., Lewis, J., Mcmenamin, R., Murray, C.W., O'Brien, M.A., Parra, L., Patel, S., Phillips, T., Rees, D.C., Rich, S., Smith, D., Trewartha, G., Vinkovic, M., Williams, B., Woolford, A.J.
J.Med.Chem.
