PDB Information

PDB2X2M
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors.
Mologni, L., Rostagno, R., Brussolo, S., Knowles, P.P., Kjaer, S., Murray-Rust, J., Rosso, E., Zambon, A., Scapozza, L., McDonald, N.Q., Lucchini, V., Gambacorti-Passerini, C.
Bioorg. Med. Chem.
HeaderTransferase
Released2010-01-13
Resolution2.500
CATH Insert Date11 Feb, 2010

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Feb, 2010 Chopped
B 11 Feb, 2010 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2x2mA01 18 Feb, 2010 3.30.200.20 Assigned
2x2mA02 18 Feb, 2010 1.10.510.10 Assigned
2x2mB01 18 Feb, 2010 3.30.200.20 Assigned
2x2mB02 18 Feb, 2010 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P07949 RET_HUMAN Homo sapiens Proto-oncogene tyrosine-protein kinase receptor Ret
P07949 RET_HUMAN Homo sapiens Proto-oncogene tyrosine-protein kinase receptor Ret
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