PDB 2x1n
PDB Information
| PDB | 2X1N |
| Method | X-RAY DIFFRACTION |
| Host Organism | SPODOPTERA FRUGIPERDA |
| Gene Source | HOMO SAPIENS |
| Primary Citation | Design, Synthesis, and Evaluation of 2-Methyl- and 2-Amino-N-Aryl-4,5-Dihydrothiazolo[4,5-H]Quinazolin-8-Amines as Ring-Constrained 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Cyclin-Dependent Kinase Inhibitors.
J.Med.Chem.
|
| Header | Cell Cycle |
| Released | 2009-12-31 |
| Resolution | 2.750 |
| CATH Insert Date | 18 Feb, 2010 |
PDB Images (14)
2x1n
PDB 2x1n
2x1nA
PDB Chain 2x1nA
2x1nB
PDB Chain 2x1nB
2x1nC
PDB Chain 2x1nC
2x1nD
PDB Chain 2x1nD
2x1nH
PDB Chain 2x1nH
2x1nA01
CATH Domain 2x1nA01
2x1nA02
CATH Domain 2x1nA02
2x1nB01
CATH Domain 2x1nB01
2x1nB02
CATH Domain 2x1nB02
2x1nC01
CATH Domain 2x1nC01
2x1nC02
CATH Domain 2x1nC02
2x1nD01
CATH Domain 2x1nD01
2x1nD02
CATH Domain 2x1nD02
PDB Prints
PDB Chains (5)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 18 Feb, 2010 | Chopped |
| B | 18 Feb, 2010 | Chopped |
| C | 18 Feb, 2010 | Chopped |
| D | 18 Feb, 2010 | Chopped |
| H | 18 Feb, 2010 | Rejected |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 2x1nA01 | 21 Feb, 2010 | 3.30.200.20 | Assigned |
| 2x1nA02 | 21 Feb, 2010 | 1.10.510.10 | Assigned |
| 2x1nB01 | 21 Feb, 2010 | 1.10.472.10 | Assigned |
| 2x1nB02 | 21 Feb, 2010 | 1.10.472.10 | Assigned |
| 2x1nC01 | 21 Feb, 2010 | 3.30.200.20 | Assigned |
| 2x1nC02 | 21 Feb, 2010 | 1.10.510.10 | Assigned |
| 2x1nD01 | 21 Feb, 2010 | 1.10.472.10 | Assigned |
| 2x1nD02 | 21 Feb, 2010 | 1.10.472.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P24941 | CDK2_HUMAN | Homo sapiens | Cyclin-dependent kinase 2 |
| P24941 | CDK2_HUMAN | Homo sapiens | Cyclin-dependent kinase 2 |
| P20248 | CCNA2_HUMAN | Homo sapiens | Cyclin-A2 |
| P20248 | CCNA2_HUMAN | Homo sapiens | Cyclin-A2 |
