PDB Information

PDB2WO9
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
The Identification of Beta-Hydroxy Carboxylic Acids as Selective Mmp-12 Inhibitors.
Holmes, I.P., Gaines, S., Watson, S.P., Lorthioir, O., Walker, A., Baddeley, S.J., Herbert, S., Egan, D., Convery, M.A., Singh, O.M.P., Gross, J.W., Strelow, J.M., Smith, R.H., Amour, A.J., Brown, D., Martin, S.L.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-07-22
Resolution1.700
CATH Insert Date10 Sep, 2009

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 10 Sep, 2009 Chopped
B 10 Sep, 2009 Chopped
C 10 Sep, 2009 Chopped
D 10 Sep, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2wo9A00 18 Mar, 2011 3.40.390.10 Assigned
2wo9B00 18 Mar, 2011 3.40.390.10 Assigned
2wo9C00 18 Mar, 2011 3.40.390.10 Assigned
2wo9D00 18 Mar, 2011 3.40.390.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P39900 MMP12_HUMAN Homo sapiens Macrophage metalloelastase
P39900 MMP12_HUMAN Homo sapiens Macrophage metalloelastase
P39900 MMP12_HUMAN Homo sapiens Macrophage metalloelastase
P39900 MMP12_HUMAN Homo sapiens Macrophage metalloelastase