PDB 2w2o

PDB Links
Overview

PDB Information

PDB	2W2O
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants. Bottomley, M.J., Cirillo, A., Orsatti, L., Ruggeri, L., Fisher, T.S., Santoro, J.C., Cummings, R.T., Cubbon, R.M., Lo Surdo, P., Calzetta, A., Noto, A., Baysarowich, J., Mattu, M., Talamo, F., De Francesco, R., Sparrow, C.P., Sitlani, A., Carfi, A. J.Biol.Chem.
Header	Hydrolase/Receptor
Released	2008-11-03
Resolution	2.620
CATH Insert Date	20 Nov, 2008

PDB Images (7)

Image of CATH 2w2o

2w2o

PDB 2w2o

Image of CATH 2w2oA

2w2oA

PDB Chain 2w2oA

Image of CATH 2w2oE

2w2oE

PDB Chain 2w2oE

Image of CATH 2w2oP

2w2oP

PDB Chain 2w2oP

Image of CATH 2w2oA00

2w2oA00

CATH Domain 2w2oA00

Image of CATH 2w2oE00

2w2oE00

CATH Domain 2w2oE00

Image of CATH 2w2oP01

2w2oP01

CATH Domain 2w2oP01

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	20 Nov, 2008	Chopped
E	20 Nov, 2008	Chopped
P	20 Nov, 2008	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2w2oA00	21 Nov, 2008	3.40.50.200	Assigned
2w2oE00	01 Jul, 2013	2.10.25.10	Assigned
2w2oP01	04 Feb, 2013	3.30.70.80	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
P01130	LDLR_HUMAN	Homo sapiens	Low-density lipoprotein receptor