PDB 2w2n

PDB Links
Overview

PDB Information

PDB	2W2N
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants. Bottomley, M.J., Cirillo, A., Orsatti, L., Ruggeri, L., Fisher, T.S., Santoro, J.C., Cummings, R.T., Cubbon, R.M., Lo Surdo, P., Calzetta, A., Noto, A., Baysarowich, J., Mattu, M., Talamo, F., De Francesco, R., Sparrow, C.P., Sitlani, A., Carfi, A. J.Biol.Chem.
Header	Hydrolase/Receptor
Released	2008-11-03
Resolution	2.300
CATH Insert Date	20 Nov, 2008

PDB Images (7)

Image of CATH 2w2n

2w2n

PDB 2w2n

Image of CATH 2w2nA

2w2nA

PDB Chain 2w2nA

Image of CATH 2w2nE

2w2nE

PDB Chain 2w2nE

Image of CATH 2w2nP

2w2nP

PDB Chain 2w2nP

Image of CATH 2w2nA00

2w2nA00

CATH Domain 2w2nA00

Image of CATH 2w2nE00

2w2nE00

CATH Domain 2w2nE00

Image of CATH 2w2nP01

2w2nP01

CATH Domain 2w2nP01

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	20 Nov, 2008	Chopped
E	20 Nov, 2008	Chopped
P	20 Nov, 2008	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2w2nA00	21 Nov, 2008	3.40.50.200	Assigned
2w2nE00	01 Jul, 2013	2.10.25.10	Assigned
2w2nP01	04 Feb, 2013	3.30.70.80	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
P01130	LDLR_HUMAN	Homo sapiens	Low-density lipoprotein receptor
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9