PDB Information

PDB2W1H
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity.
Howard, S., Berdini, V., Boulstridge, J.A., Carr, M.G., Cross, D.M., Curry, J., Devine, L.A., Early, T.R., Fazal, L., Gill, A.L., Heathcote, M., Maman, S., Matthews, J.E., Mcmenamin, R.L., Navarro, E.F., O'Brien, M.A., O'Reilly, M., Rees, D.C., Reule, M., Tisi, D., Williams, G., Vinkovic, M., Wyatt, P.G.
J.Med.Chem.
HeaderTransferase
Released2008-10-17
Resolution2.150
CATH Insert Date29 Jan, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jan, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2w1hA01 18 Feb, 2009 3.30.200.20 Assigned
2w1hA02 18 Feb, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
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