PDB Information

PDB2VIP
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Fragment-Based Discovery of Mexiletine Derivatives as Orally Bioavailable Inhibitors of Urokinase-Type Plasminogen Activator
Frederickson, M., Callaghan, O., Chessari, G., Congreve, M., Cowan, S.R., Matthews, J.E., Mcmenamin, R., Smith, D., Vinkovic, M., Wallis, N.G.
J.Med.Chem.
HeaderHydrolase
Released2007-12-05
Resolution1.720
CATH Insert Date24 Jan, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2vipA01 25 Jan, 2008 2.40.10.10 Assigned
2vipA02 25 Jan, 2008 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00749 UROK_HUMAN Homo sapiens Urokinase-type plasminogen activator
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