PDB 2uzw

PDB Information

PDB2UZW
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceBOS TAURUS
Primary Citation
Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
Zhu, G.D., Gandhi, V.B., Gong, J., Thomas, S., Woods, K.W., Song, X., Li, T., Diebold, R.B., Luo, Y., Liu, X., Guan, R., Klinghofer, V., Johnson, E.F., Bouska, J., Olson, A., Marsh, K.C., Stoll, V.S., Mamo, M., Polakowski, J., Campbell, T.J., Martin, R.L., Gintant, G.A., Penning, T.D., Li, Q., Rosenberg, S.H., Giranda, V.L.
J.Med.Chem.
HeaderTransferase
Released2007-05-01
Resolution2.200
CATH Insert Date07 Jun, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
E 07 Jun, 2007 Chopped
I 07 Jun, 2007 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2uzwE01 08 Dec, 2008 1.10.510.10 Assigned
2uzwE02 08 Dec, 2008 3.30.200.20 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00517 KAPCA_BOVIN Bos taurus cAMP-dependent protein kinase catalytic subunit alpha